Glyma.11g117100

SoyBase SoyBase transitions to NEW site on 10/1/2024
Integrating Genetics and Genomics to Advance Soybean Research

Warning: get_headers(): php_network_getaddresses: getaddrinfo for bar.utoronto.ca failed: Temporary failure in name resolution in /var/www/html/include/SeqFeatClass.php on line 1018

Warning: get_headers(https://bar.utoronto.ca/api/efp_image/efp_soybean/soybean/Absolute/Glyma.11g117100): Failed to open stream: php_network_getaddresses: getaddrinfo for bar.utoronto.ca failed: Temporary failure in name resolution in /var/www/html/include/SeqFeatClass.php on line 1018

Warning: Trying to access array offset on false in /var/www/html/include/SeqFeatClass.php on line 1019

Warning: get_headers(): php_network_getaddresses: getaddrinfo for bar.utoronto.ca failed: Temporary failure in name resolution in /var/www/html/include/SeqFeatClass.php on line 1020

Warning: get_headers(https://bar.utoronto.ca/api/efp_image/efp_soybean/soybean_severin/Absolute/Glyma.11g117100): Failed to open stream: php_network_getaddresses: getaddrinfo for bar.utoronto.ca failed: Temporary failure in name resolution in /var/www/html/include/SeqFeatClass.php on line 1020

Warning: Trying to access array offset on false in /var/www/html/include/SeqFeatClass.php on line 1021

Deprecated: preg_match(): Passing null to parameter #2 ($subject) of type string is deprecated in /var/www/html/include/SeqFeatClass.php on line 1025

Deprecated: preg_match(): Passing null to parameter #2 ($subject) of type string is deprecated in /var/www/html/include/SeqFeatClass.php on line 1031

Report for Sequence Feature Glyma.11g117100

Feature Type:	gene_model
Chromosome:	Gm11
Start:	8899120
stop:	8902345
Source:	JGI
Version:	Wm82.a2.v1
High confidence:	yes

A previous version of this gene model can be found here:

Annotations for Glyma.11g117100

Database ID	Annotation Type	Annotation Description	Annotation Source	Match Score	Evidence Code
AT1G68920.3	AT	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	JGI	N/A	IEA
AT4G34530.1	AT	cryptochrome-interacting basic-helix-loop-helix 1	JGI	N/A	IEA
GO:0016020	GO-cc	membrane	EnsemblGenomes	N/A	IEA
GO:0016021	GO-cc	integral component of membrane	EnsemblGenomes	N/A	IEA
GO:0046983	GO-mf	protein dimerization activity	EnsemblGenomes	N/A	IEA
GO:0046983	GO-mf	protein dimerization activity	JGI	N/A	IEA
PTHR12565	Panther	STEROL REGULATORY ELEMENT-BINDING PROTEIN	JGI	N/A	IEA
PTHR12565:SF7	Panther		JGI	N/A	IEA
PF00010	PFAM	Helix-loop-helix DNA-binding domain	JGI	N/A	IEA

Proteins Associated with Glyma.11g117100

Locus	Gene Symbol	Protein Name
	CIB1	basic helix-loop-helix transcription activator CIB1

Expression Patterns of Glyma.11g117100

Gene expression representations made with eFP at the University of Toronto.
Waese et al. 2017, Plant Cell 29(8):1806-1821 ePlant: Visualizing and Exploring Multiple Levels of Data for Hypothesis Generation in Plant Biology

Glyma.11g117100 not represented in the dataset	Glyma.11g117100 not represented in the dataset
Libault et al. 2010, Plant Phys 152(2):541-552. Complete Transcriptome of the Soybean Root Hair Cell, a Single-Cell Model, and Its Alteration in Response to Bradyrhizobium japonicum Infection	Severin et al. 2010, BMC Plant Biology 10:160 RNA-Seq Atlas of Glycine max: A guide to the soybean transcriptome

To see more experiments click HERE

Related Legume Genes

Gene families from Phytozome are displayed using the PhyloTree viewer developed by LIS.

Gene information in GlycineMine developed by LIS.

Related Plant Genes

Gene families from PhyloGenes.

Paralogs of Glyma.11g117100

Paralog	Evidence	Comments
Glyma.12g042800	IGC	Paralogs in soybean determined by Steven Cannon using BLAST, DAGChainer, PAML, and selection of gene pairs from synteny blocks with median Ks values of less than 0.35.

Gene model name correspondences to Glyma.11g117100 Gene Call Version Wm82.a2.v1

Corresponding Name	Annotation Version	Evidence	Comments
Glyma11g12450	Wm82.a1.v1.1	IGC	As supplied by JGI

Transcripts of Glyma.11g117100

Limit To All Plant Sequences

>Glyma.11g117100.2 sequence-type=transcript locus=Glyma.11g117100 ID=Glyma.11g117100.2.Wm82.a2.v1 annot-version=Wm82.a2.v1
ACGAAACAAATATAATATAATCTTCCCACGTTTATATATACCCACTCCTATCCCTCTCCTCATCCTTAACAACATTTCACGCTTCCTCCTCCTCTGTTTCTCTCGCACACTCTGACCCTACGTCGTTTTTTCTTTTTGTTTTCCAAACACACACACACCGCGTACTACAACTACAACAACGCCGTGCCTAATCCTTAAGAATAACAAACAACAGCCAACCATGTTGCATTGTCTCAACACTTCGGGGAATCTAGGAGCCACCTGTTCGGACATGACAGTGTTGGAAAGACAACGGGAAGCAACCATCAAGTGGCAGCAACACCTCCAGAACAACCAACCACCCTACTTAACGGACTTTAACGTTAACGTTAACGCCGtcttctcttcttcttcttcttcttctCAGAGTCAGGGCCTGGTCATGAATATTTGCGCTGATTCCGCGCTCGGCGAGGTCCTAACTCACTCCGTCAAACCCGACCCGGGTGTCTGGCCCGAATTCGACGCCGGATTCGGATCCTCTTCCGGTTTTCTACCCACCATTTCGCCAACTTGTAGCAGAGGCGGAGACTTGGTTTCACCCAAGGAAAACATGGCCAGTGCGAAAGAAAACACTAAGAAGAGAAAACCTCAGAACTCCAAGGTTGTTGCGGCGAGTGATAATAAACAGGACAAGAGAGTCAAAGCAAGTGGTGAAGAAGGAGAATCCAAAGTAACAGAGCAAACCAGCAACAAGAATGGCAAATCCAACGCAAATAAAAACAACAACAGAGAAACAACCTCTGCGGAGACTTCCAAGGATAATTCGAAAGGCTCCGAGGTTCAAAATCAGAAGCCAGAGTACATTCATGTCCGAGCGCGTCGTGGACAAGCCACGGATAGTCATAGCTTAGCTGAAAGAGTTAGGAGGGAGAAGATTAGTGAGAGAATGAAGTATTTGCAAGATTTAGTACCGGGTTGCAACAAAGTTGCAGGGAAAGCTGGAATGCTTGATGAAATTATTAACTATGTTCAGTCTCTTCAACGCCAAGTTGAGTTCTTGTCAATGAAATTAGCGGCTGTAAACCCAAGGCTTGACTTCAACCTTGACGAACTATTTACCAAAGAGGTGTTTCCTTCTTGTGCTCAAAGTTTTCCAAACATTGGGATGCCATTAGATATGAGTATGAGTAACAACCCTTCGTATCTACCATTTAATTCAGCGCAGCAACTTGTATCGTGCTGTGGTGGACTAATAAACAACATGGGGATAAGCCCTCCAAACATGGGACTCCGAAGGAACATTAGTACTAGCCCTGTACCTTTGCCCGAAACGTTTCTTGACTCGTCCTGTTTCACTCAAATTCTACCCTCCTCAAATTGGGAAGGTGGTGATTTCCAAAGCCTTTACAACGTTGCTTTTGATCAAGGGCGAACAGCATCTTTTCCTTCTCAGCCATTTACAGGTCTAGTTGAAGCTAGCAATCTAAAGATGGAGATGTAAACCAGATCGATCATCCATTATAATTTGTTGGTGGATTAGGTCACTCGGAGTGCCTTTGTCATGATTTTTTCTTTTTTCTTTTTTCGAGTACATAACATATATTGGTTGTATACTGCTCCGTAGAATAAATAAGATCATATTAATACCTGTTAACTTCAATCACCTGCATTTGCACGTTTAAAGTACTatatagatgataataaaaagaaaaataaaataaaaatgaaaaGGTT

>Glyma.11g117100.3 sequence-type=transcript locus=Glyma.11g117100 ID=Glyma.11g117100.3.Wm82.a2.v1 annot-version=Wm82.a2.v1
ACGAAACAAATATAATATAATCTTCCCACGTTTATATATACCCACTCCTATCCCTCTCCTCATCCTTAACAACATTTCACGCTTCCTCCTCCTCTGTTTCTCTCGCACACTCTGACCCTACGTCGTTTTTTCTTTTTGTTTTCCAAACACACACACACCGCGTACTACAACTACAACAACGCCGTGCCTAATCCTTAAGAATAACAAACAACAGCCAACCATGTTGCATTGTCTCAACACTTCGGGGAATCTAGGAGCCACCTGTTCGGACATGACAGTGTTGGAAAGACAACGGGAAGCAACCATCAAGTGGCAGCAACACCTCCAGAACAACCAACCACCCTACTTAACGGACTTTAACGTTAACGTTAACGCCGtcttctcttcttcttcttcttcttctCAGAGTCAGGGCCTGGTCATGAATATTTGCGCTGATTCCGCGCTCGGCGAGGTCCTAACTCACTCCGTCAAACCCGACCCGGGTGTCTGGCCCGAATTCGACGCCGGATTCGGATCCTCTTCCGGTTTTCTACCCACCATTTCGCCAACTTGTAGCAGAGGCGGAGACTTGGTTTCACCCAAGGAAAACATGGCCAGTGCGAAAGAAAACACTAAGAAGAGAAAACCTCAGAACTCCAAGGTTGTTGCGGCGAGTGATAATAAACAGGACAAGAGAGTCAAAGCAAGTGGTGAAGAAGGAGAATCCAAAGTAACAGAGCAAACCAGCAACAAGAATGGCAAATCCAACGCAAATAAAAACAACAACAGAGAAACAACCTCTGCGGAGACTTCCAAGGATAATTCGAAAGGCTCCGAGGTTCAAAATCAGAAGCCAGAGTACATTCATGTCCGAGCGCGTCGTGGACAAGCCACGGATAGTCATAGCTTAGCTGAAAGAGTTAGGAGGGAGAAGATTAGTGAGAGAATGAAGTATTTGCAAGATTTAGTACCGGGTTGCAACAAAGTTGCAGGGAAAGCTGGAATGCTTGATGAAATTATTAACTATGTTCAGTCTCTTCAACGCCAAGTTGAGTTCTTGTCAATGAAATTAGCGGCTGTAAACCCAAGGCTTGACTTCAACCTTGACGAACTATTTACCAAAGAGGTGTTTCCTTCTTGTGCTCAAAGTTTTCCAAACATTGGGATGCCATTAGATATGAGTATGAGTAACAACCCTTCGTATCTACCATTTAATTCAGCGCAGCAACTTGTATCGTGCTGTGGTGGACTAATAAACAACATGGGGATAAGCCCTCCAAACATGGGACTCCGAAGGAACATTAGTACTAGCCCTGTACCTTTGCCCGAAACGTTTCTTGACTCGTCCTGTTTCACTGTAGGTTTTTTTACCCTCTCTTGTGTATGTAATGTTCTTCTAATGATTAGTCTTGTCCAAATATTGATCTGAATTTTTTTGCACTGCAGCAAATTCTACCCTCCTCAAATTGGGAAGGTGGTGATTTCCAAAGCCTTTACAACGTTGCTTTTGATCAAGGGCGAACAGCATCTTTTCCTTCTCAGCCATTTACAGGTCTAGTTGAAGCTAGCAATCTAAAGATGGAGATGTAAACCAGATCGATCATCCATTATAATTTGTTGGTGGATTAGGTCACTCGGAGTGCCTTTGTCATGATTTTTTCTTTTTTCTTTTTTCGAGTACATAACATATATTGGTTGTATACTGCTCCGTAGAATAAATAAGATCATATTAATACCTGTTAACTTCAATCACCTGCATTTGCACGTTTAAAGTACTatatagatgataataaaaagaaaaataaaataaaaatgaaaaGGTT

Coding sequences of Glyma.11g117100

Limit To All Plant Sequences

>Glyma.11g117100.1 sequence-type=CDS polypeptide=Glyma.11g117100.1.p locus=Glyma.11g117100 ID=Glyma.11g117100.1.Wm82.a2.v1 annot-version=Wm82.a2.v1
ATGTTGCATTGTCTCAACACTTCGGGGAATCTAGGAGCCACCTGTTCGGACATGACAGTGTTGGAAAGACAACGGGAAGCAACCATCAAGTGGCAGCAACACCTCCAGAACAACCAACCACCCTACTTAACGGACTTTAACGTTAACGTTAACGCCGTCTTCTCTTCTTCTTCTTCTTCTTCTCAGAGTCAGGGCCTGGTCATGAATATTTGCGCTGATTCCGCGCTCGGCGAGGTCCTAACTCACTCCGTCAAACCCGACCCGGGTGTCTGGCCCGAATTCGACGCCGGATTCGGATCCTCTTCCGGTTTTCTACCCACCATTTCGCCAACTTGTAGCAGAGGCGGAGACTTGGTTTCACCCAAGGAAAACATGGCCAGTGCGAAAGAAAACACTAAGAAGAGAAAACCTCAGAACTCCAAGGTAGTTGTTGCGGCGAGTGATAATAAACAGGACAAGAGAGTCAAAGCAAGTGGTGAAGAAGGAGAATCCAAAGTAACAGAGCAAACCAGCAACAAGAATGGCAAATCCAACGCAAATAAAAACAACAACAGAGAAACAACCTCTGCGGAGACTTCCAAGGATAATTCGAAAGGCTCCGAGGTTCAAAATCAGAAGCCAGAGTACATTCATGTCCGAGCGCGTCGTGGACAAGCCACGGATAGTCATAGCTTAGCTGAAAGAGTTAGGAGGGAGAAGATTAGTGAGAGAATGAAGTATTTGCAAGATTTAGTACCGGGTTGCAACAAAGTTGCAGGGAAAGCTGGAATGCTTGATGAAATTATTAACTATGTTCAGTCTCTTCAACGCCAAGTTGAGTTCTTGTCAATGAAATTAGCGGCTGTAAACCCAAGGCTTGACTTCAACCTTGACGAACTATTTACCAAAGAGGTGTTTCCTTCTTGTGCTCAAAGTTTTCCAAACATTGGGATGCCATTAGATATGAGTATGAGTAACAACCCTTCGTATCTACCATTTAATTCAGCGCAGCAACTTGTATCGTGCTGTGGTGGACTAATAAACAACATGGGGATAAGCCCTCCAAACATGGGACTCCGAAGGAACATTAGTACTAGCCCTGTACCTTTGCCCGAAACGTTTCTTGACTCGTCCTGTTTCACTCAAATTCTACCCTCCTCAAATTGGGAAGGTGGTGATTTCCAAAGCCTTTACAACGTTGCTTTTGATCAAGGGCGAACAGCATCTTTTCCTTCTCAGCCATTTACAGGTCTAGTTGAAGCTAGCAATCTAAAGATGGAGATGTAA

>Glyma.11g117100.2 sequence-type=CDS polypeptide=Glyma.11g117100.2.p locus=Glyma.11g117100 ID=Glyma.11g117100.2.Wm82.a2.v1 annot-version=Wm82.a2.v1
ATGTTGCATTGTCTCAACACTTCGGGGAATCTAGGAGCCACCTGTTCGGACATGACAGTGTTGGAAAGACAACGGGAAGCAACCATCAAGTGGCAGCAACACCTCCAGAACAACCAACCACCCTACTTAACGGACTTTAACGTTAACGTTAACGCCGTCTTCTCTTCTTCTTCTTCTTCTTCTCAGAGTCAGGGCCTGGTCATGAATATTTGCGCTGATTCCGCGCTCGGCGAGGTCCTAACTCACTCCGTCAAACCCGACCCGGGTGTCTGGCCCGAATTCGACGCCGGATTCGGATCCTCTTCCGGTTTTCTACCCACCATTTCGCCAACTTGTAGCAGAGGCGGAGACTTGGTTTCACCCAAGGAAAACATGGCCAGTGCGAAAGAAAACACTAAGAAGAGAAAACCTCAGAACTCCAAGGTTGTTGCGGCGAGTGATAATAAACAGGACAAGAGAGTCAAAGCAAGTGGTGAAGAAGGAGAATCCAAAGTAACAGAGCAAACCAGCAACAAGAATGGCAAATCCAACGCAAATAAAAACAACAACAGAGAAACAACCTCTGCGGAGACTTCCAAGGATAATTCGAAAGGCTCCGAGGTTCAAAATCAGAAGCCAGAGTACATTCATGTCCGAGCGCGTCGTGGACAAGCCACGGATAGTCATAGCTTAGCTGAAAGAGTTAGGAGGGAGAAGATTAGTGAGAGAATGAAGTATTTGCAAGATTTAGTACCGGGTTGCAACAAAGTTGCAGGGAAAGCTGGAATGCTTGATGAAATTATTAACTATGTTCAGTCTCTTCAACGCCAAGTTGAGTTCTTGTCAATGAAATTAGCGGCTGTAAACCCAAGGCTTGACTTCAACCTTGACGAACTATTTACCAAAGAGGTGTTTCCTTCTTGTGCTCAAAGTTTTCCAAACATTGGGATGCCATTAGATATGAGTATGAGTAACAACCCTTCGTATCTACCATTTAATTCAGCGCAGCAACTTGTATCGTGCTGTGGTGGACTAATAAACAACATGGGGATAAGCCCTCCAAACATGGGACTCCGAAGGAACATTAGTACTAGCCCTGTACCTTTGCCCGAAACGTTTCTTGACTCGTCCTGTTTCACTCAAATTCTACCCTCCTCAAATTGGGAAGGTGGTGATTTCCAAAGCCTTTACAACGTTGCTTTTGATCAAGGGCGAACAGCATCTTTTCCTTCTCAGCCATTTACAGGTCTAGTTGAAGCTAGCAATCTAAAGATGGAGATGTAA

>Glyma.11g117100.3 sequence-type=CDS polypeptide=Glyma.11g117100.3.p locus=Glyma.11g117100 ID=Glyma.11g117100.3.Wm82.a2.v1 annot-version=Wm82.a2.v1
ATGTTGCATTGTCTCAACACTTCGGGGAATCTAGGAGCCACCTGTTCGGACATGACAGTGTTGGAAAGACAACGGGAAGCAACCATCAAGTGGCAGCAACACCTCCAGAACAACCAACCACCCTACTTAACGGACTTTAACGTTAACGTTAACGCCGTCTTCTCTTCTTCTTCTTCTTCTTCTCAGAGTCAGGGCCTGGTCATGAATATTTGCGCTGATTCCGCGCTCGGCGAGGTCCTAACTCACTCCGTCAAACCCGACCCGGGTGTCTGGCCCGAATTCGACGCCGGATTCGGATCCTCTTCCGGTTTTCTACCCACCATTTCGCCAACTTGTAGCAGAGGCGGAGACTTGGTTTCACCCAAGGAAAACATGGCCAGTGCGAAAGAAAACACTAAGAAGAGAAAACCTCAGAACTCCAAGGTTGTTGCGGCGAGTGATAATAAACAGGACAAGAGAGTCAAAGCAAGTGGTGAAGAAGGAGAATCCAAAGTAACAGAGCAAACCAGCAACAAGAATGGCAAATCCAACGCAAATAAAAACAACAACAGAGAAACAACCTCTGCGGAGACTTCCAAGGATAATTCGAAAGGCTCCGAGGTTCAAAATCAGAAGCCAGAGTACATTCATGTCCGAGCGCGTCGTGGACAAGCCACGGATAGTCATAGCTTAGCTGAAAGAGTTAGGAGGGAGAAGATTAGTGAGAGAATGAAGTATTTGCAAGATTTAGTACCGGGTTGCAACAAAGTTGCAGGGAAAGCTGGAATGCTTGATGAAATTATTAACTATGTTCAGTCTCTTCAACGCCAAGTTGAGTTCTTGTCAATGAAATTAGCGGCTGTAAACCCAAGGCTTGACTTCAACCTTGACGAACTATTTACCAAAGAGGTGTTTCCTTCTTGTGCTCAAAGTTTTCCAAACATTGGGATGCCATTAGATATGAGTATGAGTAACAACCCTTCGTATCTACCATTTAATTCAGCGCAGCAACTTGTATCGTGCTGTGGTGGACTAATAAACAACATGGGGATAAGCCCTCCAAACATGGGACTCCGAAGGAACATTAGTACTAGCCCTGTACCTTTGCCCGAAACGTTTCTTGACTCGTCCTGTTTCACTGTAGGTTTTTTTACCCTCTCTTGTGTATGTAATGTTCTTCTAATGATTAGTCTTGTCCAAATATTGATCTGA

Predicted protein sequences of Glyma.11g117100

Limit To All Plant Sequences

>Glyma.11g117100.1.p sequence-type=predicted peptide transcript=Glyma.11g117100.1 locus=Glyma.11g117100 ID=Glyma.11g117100.1.Wm82.a2.v1 annot-version=Wm82.a2.v1
MLHCLNTSGNLGATCSDMTVLERQREATIKWQQHLQNNQPPYLTDFNVNVNAVFSSSSSSSQSQGLVMNICADSALGEVLTHSVKPDPGVWPEFDAGFGSSSGFLPTISPTCSRGGDLVSPKENMASAKENTKKRKPQNSKVVVAASDNKQDKRVKASGEEGESKVTEQTSNKNGKSNANKNNNRETTSAETSKDNSKGSEVQNQKPEYIHVRARRGQATDSHSLAERVRREKISERMKYLQDLVPGCNKVAGKAGMLDEIINYVQSLQRQVEFLSMKLAAVNPRLDFNLDELFTKEVFPSCAQSFPNIGMPLDMSMSNNPSYLPFNSAQQLVSCCGGLINNMGISPPNMGLRRNISTSPVPLPETFLDSSCFTQILPSSNWEGGDFQSLYNVAFDQGRTASFPSQPFTGLVEASNLKMEM*

>Glyma.11g117100.2.p sequence-type=predicted peptide transcript=Glyma.11g117100.2 locus=Glyma.11g117100 ID=Glyma.11g117100.2.Wm82.a2.v1 annot-version=Wm82.a2.v1
MLHCLNTSGNLGATCSDMTVLERQREATIKWQQHLQNNQPPYLTDFNVNVNAVFSSSSSSSQSQGLVMNICADSALGEVLTHSVKPDPGVWPEFDAGFGSSSGFLPTISPTCSRGGDLVSPKENMASAKENTKKRKPQNSKVVAASDNKQDKRVKASGEEGESKVTEQTSNKNGKSNANKNNNRETTSAETSKDNSKGSEVQNQKPEYIHVRARRGQATDSHSLAERVRREKISERMKYLQDLVPGCNKVAGKAGMLDEIINYVQSLQRQVEFLSMKLAAVNPRLDFNLDELFTKEVFPSCAQSFPNIGMPLDMSMSNNPSYLPFNSAQQLVSCCGGLINNMGISPPNMGLRRNISTSPVPLPETFLDSSCFTQILPSSNWEGGDFQSLYNVAFDQGRTASFPSQPFTGLVEASNLKMEM*

>Glyma.11g117100.3.p sequence-type=predicted peptide transcript=Glyma.11g117100.3 locus=Glyma.11g117100 ID=Glyma.11g117100.3.Wm82.a2.v1 annot-version=Wm82.a2.v1
MLHCLNTSGNLGATCSDMTVLERQREATIKWQQHLQNNQPPYLTDFNVNVNAVFSSSSSSSQSQGLVMNICADSALGEVLTHSVKPDPGVWPEFDAGFGSSSGFLPTISPTCSRGGDLVSPKENMASAKENTKKRKPQNSKVVAASDNKQDKRVKASGEEGESKVTEQTSNKNGKSNANKNNNRETTSAETSKDNSKGSEVQNQKPEYIHVRARRGQATDSHSLAERVRREKISERMKYLQDLVPGCNKVAGKAGMLDEIINYVQSLQRQVEFLSMKLAAVNPRLDFNLDELFTKEVFPSCAQSFPNIGMPLDMSMSNNPSYLPFNSAQQLVSCCGGLINNMGISPPNMGLRRNISTSPVPLPETFLDSSCFTVGFFTLSCVCNVLLMISLVQILI*

Funded by the USDA-ARS. Developed by the USDA-ARS SoyBase and Legume Clade Database group at the Iowa State University, Ames, IA

U.S. Public Domain